ABSTRACT
Objective@#To investigate the occurrence of masked hypertension (MH) and the degree of damage to target organs in people with family history of hypertension.@*Methods@#987 cases of family history of hypertension who had been examined in our hospital from January 2017 to November 2017 were selected as observation group with the approval of hospital ethics committee. At the same time, 987 subjects without family history of hypertension who had been examined in our hospital during the same period were selected as control group. The incidence of masked hypertension, left ventricular mass index (LVMI) and carotid intima-media thickness (IMT) were observed.@*Results@#The incidence of hypertension and masked hypertension in the observation group was significantly higher than that in the control group (P<0.05). LVMI and IMT in patients with masked hypertension were significantly higher than those in normal blood pressure group. LVMI and IMT in patients with hypertension were higher than those in patients with masked hypertension and normal blood pressure group. The LVMI and IMT of patients with family history of masked hypertension were higher than those without family history of masked hypertension.@*Conclusions@#Family history of hypertension can increase the incidence of masked hypertension and organ damage of patients. The monitoring of masked hypertension should be strengthened for those with family history of hypertension.
ABSTRACT
Objective To investigate the occurrence of masked hypertension (MH) and the degree of damage to target organs in people with family history of hypertension.Methods 987 cases of family history of hypertension who had been examined in our hospital from January 2017 to November 2017 were selected as observation group with the approval of hospital ethics committee.At the same time,987 subjects without family history of hypertension who had been examined in our hospital during the same period were selected as control group.The incidence of masked hypertension,left ventricular mass index (LVMI) and carotid intima-media thickness (IMT) were observed.Results The incidence of hypertension and masked hypertension in the observation group was significantly higher than that in the control group (P ＜ 0.05).LVMI and IMT in patients with masked hypertension were significantly higher than those in normal blood pressure group.LVMI and IMT in patients with hypertension were higher than those in patients with masked hypertension and normal blood pressure group.The LVMI and IMT of patients with family history of masked hypertension were higher than those without family history of masked hypertension.Conclusions Family history of hypertension can increase the incidence of masked hypertension and organ damage of patients.The monitoring of masked hypertension should be strengthened for those with family history of hypertension.
ABSTRACT
Objective To investigate the effects of Tongfengding capsule combined with diclofenac sodium on blood uric acid level, joint swelling and pain in gout patients. Methods 120 cases of gout patients enrolled in our hospital from January 2014 to June 2016 were selected for the study and divided into the control group and the observation group according to the random number table, with 60 cases in each group. The two groups were given anti-infection, low purine diet and other basic treatment, and both treated with sodium bicarbonate tablets and diclofenac sodium. The observation group was given Tongfengding capsule on this basis and the two groups were treated for four weeks. After treatment, gout related factors erythrocyte sedimentation rate (ESR) was observed in the two groups, and TCM symptoms of redness and swelling, pain scores were evaluated and the onset of gout was observed again at six months after treatment. Results The level of UA (463.47±50.28) CB/(μmol?L) in the control group was significantly higher than that in the control group (434.52±51.63) CB/(μmol?L) (P<0.05). The pain and swelling score of the control group were significantly higher than those in the observation group (P<0.05). The recurrence rate in the observation group (5%) was significantly lower than that in the control group (18.33%) (P<0.05). Conclusion Tongfengding capsule combined with diclofenac sodium can effectively relieve joint swelling, pain symptoms of gout patients and reduce blood uric acid levels with significant clinical efficacy.